Carlos speaks at the C^2 Summer Research Symposium
After another productive summer Carlos gave an excellent talk at the C^2 Summer Scholars Research Symposium! Last year, Carlos discovered that the installation of an active site mutation in his artificial metalloprotein (ArM) significantly enhanced cofactor binding affinity but completely obliterated catalytic activity. To understand why this is, Carlos has now teamed up with Taher to explore the computationally predicted (Taher) and experimentally defined (Carlos) protein dynamics relevant to substrate binding in the ArM. Final results are yet to go public but I promise you that the plot has thickened! Stay tuned for our next paper coming soon.